Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894463 | 0.81 | EGFR (0.57) | LMNATDP1TSHRCYP3A4ALDH1A1 | |
| SCHEMBL28158149 | 0.81 | EGFR (0.57) | LMNATDP1TSHRCYP3A4ALDH1A1 | |
| SCHEMBL9998473 | 0.80 | THRB (0.47) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL9998474 | 0.80 | THRB (0.47) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL9998121 | 0.79 | TNNC1 (0.48) | PLA2G1BLMNATDP1TP53CYP3A4 | |
| SCHEMBL9997968 | 0.79 | TNNC1 (0.48) | PLA2G1BLMNATDP1TP53CYP3A4 | |
| SCHEMBL9998273 | 0.79 | TNNC1 (0.48) | PLA2G1BLMNATDP1TP53CYP3A4 | |
| SCHEMBL9997966 | 0.79 | TNNC1 (0.48) | PLA2G1BLMNATDP1TP53CYP3A4 | |
| SCHEMBL9997695 | 0.79 | TNNC1 (0.48) | PLA2G1BLMNATDP1TP53CYP3A4 | |
| SCHEMBL9998003 | 0.79 | TNNC1 (0.48) | PLA2G1BLMNATDP1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60142936-A | — | — | None | — | — | JP | disclosed |
| JP-S60142936-A | SUBSTITUTED PHENYL DERIVATIVE, ITS PREPARATION, AND REMEDY CONTAINING IT | ONO PHARMACEUT CO LTD | 1985-07-29 | — | — | JP | disclosed |