Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 1.00 |
| ▸ | CREBBP | Q92793 | 1/20 | 1.00 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.66 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031033 | 1.00 | NR4A2 (1.00) | NR4A2CREBBPPBRM1GPR84RAB9A | |
| Hydrochloric Acid SCHEMBL28254334 | 0.98 | NR4A2 (0.97) | NR4A2CREBBPPBRM1GPR84RAB9A | |
| SCHEMBL28327513 | 0.89 | NR4A2 (0.80) | NR4A2CREBBPPBRM1GPR84RAB9A | |
| SCHEMBL21438794 | 0.89 | NR4A2 (0.79) | NR4A2CREBBPPBRM1GPR84RAB9A | |
| SCHEMBL29696613 | 0.88 | NR4A2 (0.79) | NR4A2CREBBPPBRM1GPR84RAB9A | |
| SCHEMBL2052030 | 0.88 | NR4A2 (0.79) | NR4A2CREBBPPBRM1GPR84RAB9A | |
| SCHEMBL21439506 | 0.84 | TP53 (0.74) | NR4A2CREBBPPBRM1GPR84RAB9A | |
| SCHEMBL28579575 | 0.84 | NPC1 (0.72) | NR4A2CREBBPPBRM1GPR84RAB9A | |
| SCHEMBL30658176 | 0.83 | NR4A2 (0.71) | NR4A2CREBBPPBRM1GPR84RAB9A | |
| SCHEMBL729076 | 0.83 | NR4A2 (0.71) | NR4A2CREBBPPBRM1GPR84RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 777 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119819370-A | Preparation method of photocatalytic degradation material for treating acid chrome blue K sewage | 北方工业大学 | 2025-04-15 | — | — | CN | claimed |
| CN-116332941-B | Synthesis method of lactam-indoline structure compound | 中国石油大学(华东) | 2024-04-12 | — | — | CN | claimed |
| CN-114181928-B | Immobilized microbial agent for repairing marine petroleum pollution | 浙江省海洋水产研究所 | 2023-10-31 | — | — | CN | claimed |
| US-11751573-B2 | Seaweed composition | PORT LOUIS BERNARD (SC) | 2023-09-12 | — | — | US | claimed |
| CN-116332941-A | Synthesis method of lactam-indoline structure compound | 中国石油大学(华东) | 2023-06-27 | — | — | CN | claimed |
| CN-109678810-B | 1,2-oxygen nitrogen heterocyclic butane compound and preparation method and application thereof | 南京工业大学 | 2022-10-28 | — | — | CN | claimed |
| CN-114149356-A | Preparation method of methyl indolcarbate compound | 安徽益多康尔医药科技有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-113683567-A | Synthesis method of novel estrogen receptor targeting inhibitor and application of novel estrogen receptor targeting inhibitor in breast cancer treatment | 杨锦飞 | 2021-11-23 | — | — | CN | claimed |
| CN-111269397-B | Polymerization method and polymer prepared by same | 中国科学院福建物质结构研究所 | 2021-05-11 | — | — | CN | claimed |
| CN-108409731-B | Chiral resolution of aryl-substituted 1H-pyridine [3,4-b ] indole-3-carboxylic acid methyl ester | 西华大学 | 2020-11-20 | — | — | CN | claimed |
| CN-1671706-A | Modified pictet-spengler reaction and products prepared therefrom | LILLY ICOS LLC (US) | 2005-09-21 | — | — | CN | claimed |
| CN-1633296-A | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMA (US) | 2005-06-29 | — | — | CN | claimed |
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | claimed |
| US-20040063758-A1 | INHIBITORS OF BACTERIAL NAD SYNTHETASE | BROUILLETTE WAYNE J (US) | 2004-04-01 | — | — | US | claimed |
| JP-2002509149-A | — | — | 2002-03-26 | — | — | JP | claimed |
| EP-1109805-A1 | INHIBITORS OF BACTERIAL NAD SYNTHETASE | The UAB Research Foundation (US) | 2001-06-27 | — | — | EP | claimed |
| EP-1047692-A1 | METHODS OF SYNTHESIZING AND SCREENING INHIBITORS OF BACTERIAL NAD SYNTHETASE ENZYME, COMPOUNDS THEREOF AND METHODS OF TREATING BACTERIAL AND MICROBIAL INFECTIONS WITH THESE INHIBITORS | THE UAB RESEARCH FOUNDATION (US) | 2000-11-02 | — | — | EP | claimed |
| WO-2000010996-A1 | INHIBITORS OF BACTERIAL NAD SYNTHETASE | THE UAB RESEARCH FOUNDATION (US) | 2000-03-02 | — | — | WO | claimed |
| WO-1999036422-A1 | METHODS OF SYNTHESIZING AND SCREENING INHIBITORS OF BACTERIAL NAD SYNTHETASE ENZYME, COMPOUNDS THEREOF, AND METHODS OF TREATING BACTERIAL AND MICROBIAL INFECTIONS WITH INHIBITORS OF BACTERIAL NAD SYNTHETASE ENZYME | THE UAB RESEARCH FOUNDATION (US) | 1999-07-22 | — | — | WO | claimed |
| EP-0360638-A1 | Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor | L'OREAL (FR) | 1990-03-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063758-A1 | INHIBITORS OF BACTERIAL NAD SYNTHETASE | COASY, NADK, NQO1 | NR4A2 2745/4885CREBBP 737/4885PBRM1 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.