Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.71 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CFTR | P13569 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572431 | 0.85 | NR4A2 (0.61) | NPC1KMT2AMEN1NR4A2CREBBP | |
| SCHEMBL28577422 | 0.85 | MEN1 (0.65) | NPC1KMT2AMEN1NR4A2CREBBP | |
| SCHEMBL1093530 | 0.84 | NR4A2 (1.00) | KMT2AMEN1NR4A2CREBBPMAPT | |
| SCHEMBL30031033 | 0.84 | NR4A2 (1.00) | KMT2AMEN1NR4A2CREBBPMAPT | |
| SCHEMBL28569094 | 0.84 | NR4A2 (0.63) | NPC1KMT2AMEN1NR4A2CREBBP | |
| SCHEMBL21446804 | 0.83 | ALDH1A1 (0.67) | NPC1KMT2AMEN1NR4A2CREBBP | |
| Hydrochloric Acid SCHEMBL28254334 | 0.82 | NR4A2 (0.97) | KMT2AMEN1NR4A2CREBBPMAPT | |
| SCHEMBL20567854 | 0.81 | NPC1 (0.68) | NPC1KMT2AMEN1NR4A2CREBBP | |
| SCHEMBL27075304 | 0.81 | NPC1 (0.68) | NPC1KMT2AMEN1NR4A2CREBBP | |
| SCHEMBL21438794 | 0.80 | NR4A2 (0.79) | NPC1KMT2AMEN1NR4A2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004188-B | Indole derivative, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113004188-A | Indole derivative, preparation method and application | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |