Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122148 | 0.91 | HDAC4 (0.62) | HDAC4HDAC2HDAC8ME2ME1 | |
| SCHEMBL10936706 | 0.82 | ACLY (0.55) | HDAC4HDAC2HDAC8ME2ME1 | |
| SCHEMBL10937241 | 0.82 | HDAC4 (0.53) | HDAC4HDAC2HDAC8ME2ME1 | |
| SCHEMBL10935780 | 0.82 | HDAC4 (0.53) | HDAC4HDAC2HDAC8ME2ME1 | |
| SCHEMBL10940628 | 0.82 | HDAC4 (0.53) | HDAC4HDAC2HDAC8ME2ME1 | |
| SCHEMBL11119370 | 0.81 | HDAC4 (0.59) | HDAC4HDAC2HDAC8ACLYMEN1 | |
| SCHEMBL11401528 | 0.77 | ACLY (0.50) | HDAC4HDAC2HDAC8ME2ME1 | |
| SCHEMBL10937755 | 0.77 | ACLY (0.56) | HDAC4HDAC2HDAC8ME2ME1 | |
| SCHEMBL10939753 | 0.76 | ACLY (0.55) | HDAC4HDAC2HDAC8ME2ME1 | |
| SCHEMBL10940643 | 0.76 | ACLY (0.55) | HDAC4HDAC2HDAC8ME2ME1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4532069-A | For electro-optical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-07-30 | — | — | US | disclosed |