Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | ME2 | P23368 | 1/20 | 0.44 |
| ▸ | ME1 | P48163 | 1/20 | 0.44 |
| ▸ | ME3 | Q16798 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937755 | 0.85 | ACLY (0.56) | ACLYHDAC4HDAC2HDAC8ME2 | |
| SCHEMBL11122148 | 0.84 | HDAC4 (0.62) | ACLYHDAC4HDAC2HDAC8ME2 | |
| SCHEMBL10939753 | 0.84 | ACLY (0.55) | ACLYHDAC4HDAC2HDAC8ME2 | |
| SCHEMBL10936706 | 0.84 | ACLY (0.55) | ACLYHDAC4HDAC2HDAC8ME2 | |
| SCHEMBL10940628 | 0.82 | HDAC4 (0.53) | ACLYHDAC4HDAC2HDAC8ME2 | |
| SCHEMBL11119370 | 0.81 | HDAC4 (0.59) | ACLYHDAC4HDAC2HDAC8ELANE | |
| SCHEMBL10937241 | 0.76 | HDAC4 (0.53) | ACLYHDAC4HDAC2HDAC8ME2 | |
| SCHEMBL10936340 | 0.76 | HDAC4 (0.53) | ACLYHDAC4HDAC2HDAC8ME2 | |
| SCHEMBL10935780 | 0.76 | HDAC4 (0.53) | ACLYHDAC4HDAC2HDAC8ME2 | |
| SCHEMBL11401528 | 0.72 | ACLY (0.50) | ACLYHDAC4HDAC2HDAC8ME2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4532069-A | For electro-optical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-07-30 | — | — | US | disclosed |