Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 13/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | PLG | P00747 | 4/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | KLK1 | P06870 | 2/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | C1R | P00736 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938113 | 0.79 | PLAU (0.40) | F12PRSS1F2PLGF10 | |
| SCHEMBL7344739 | 0.76 | PLAU (0.68) | F12PRSS1F2PLGF10 | |
| SCHEMBL10939558 | 0.73 | POLB (0.49) | F12PRSS1F2PLGF10 | |
| SCHEMBL10934547 | 0.73 | F12 (0.53) | F12PRSS1F2PLGF10 | |
| SCHEMBL10940056 | 0.72 | F12 (0.52) | F12PRSS1F2PLGF10 | |
| SCHEMBL31499213 | 0.72 | F12 (0.61) | F12PRSS1F2PLGF10 | |
| SCHEMBL10802088 | 0.71 | GAA (0.42) | ALDH1A1LMNAMAPT | |
| SCHEMBL7339708 | 0.71 | PLAU (0.60) | F12PRSS1F2PLGF10 | |
| SCHEMBL10936549 | 0.71 | F12 (0.46) | F12PRSS1F2PLGF10 | |
| SCHEMBL10938112 | 0.70 | F12 (0.59) | F12PRSS1F2PLGF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496584-A | ANTITRYPSIN, ANTIKALLIKREIN, ANTITHROMBIN OR ANTIPLASMIN AGENT | TORII & CO. LTD. (JP) | 1985-01-29 | — | — | US | disclosed |