Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 11/20 | 0.40 |
| ▸ | F2 | P00734 | 7/20 | 0.37 |
| ▸ | PLG | P00747 | 4/20 | 0.37 |
| ▸ | PLAT | P00750 | 4/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339710 | 0.81 | PLAU (0.60) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10936562 | 0.79 | F12 (0.46) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10937015 | 0.77 | PLAU (0.46) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10939457 | 0.77 | PLAU (0.48) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10938176 | 0.77 | PLAU (0.48) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10935567 | 0.76 | F2 (0.45) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10936200 | 0.75 | PLAU (0.45) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10940106 | 0.75 | PLAU (0.44) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10936558 | 0.74 | PLAU (0.44) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL7338914 | 0.74 | PLAU (0.50) | PLAUF2PLGPLATKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496584-A | ANTITRYPSIN, ANTIKALLIKREIN, ANTITHROMBIN OR ANTIPLASMIN AGENT | TORII & CO. LTD. (JP) | 1985-01-29 | — | — | US | disclosed |