Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939029 | 0.89 | MC4R (0.45) | MC4RCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL10507831 | 0.79 | FAAH (0.57) | CACNA2D1CACNA1BCACNB1CACNA1CLMNA | |
| Hydrochloric Acid SCHEMBL10935504 | 0.78 | KMT2A (0.61) | MC4RCACNA1CMEN1CNR1CNR2 | |
| SCHEMBL10933074 | 0.76 | CNR1 (0.50) | CACNA2D1CACNA1BCACNB1MEN1CNR1 | |
| SCHEMBL10936578 | 0.76 | KMT2A (0.47) | MEN1CNR1CNR2KMT2ASMN1; SMN2 | |
| SCHEMBL2931059 | 0.73 | CACNA2D1 (0.53) | MC4RCACNA2D1CACNA1BCACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL10936662 | 0.71 | KMT2A (0.62) | MC4RCACNA1CMEN1CNR1CNR2 | |
| SCHEMBL1760998 | 0.71 | CHRM2 (0.48) | MC4RCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL548109 | 0.71 | SLC6A9 (0.49) | MC4RCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL29710209 | 0.70 | CHRM4 (0.56) | LMNANPC1SMN1; SMN2RAB9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1985000811-A1 | NOVEL 1-PIPERAZINECARBOXAMIDE DERIVATIVES | AB FERROSAN (SE) | 1985-02-28 | — | — | WO | disclosed |