SCHEMBL10936636

SCHEMBL10936636

NP(N)(=O)Oc1cccc(OP(N)(N)=O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SRC P12931 2/20 0.42
HCRTR1 O43613 1/20 0.42
INPPL1 O15357 1/20 0.39
INPP5A Q14642 1/20 0.39
MAPT P10636 3/20 0.38
MITF O75030 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NLRP1 Q9C000 1/20 0.38
NOD2 Q9HC29 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenyl Phosphordiamidate SCHEMBL731553 0.82 L3MBTL1 (0.62) MEN1KMT2ACA1CA2CA9
SCHEMBL12447399 0.80 AKR1C3 (0.58) KMT2ACA1CA2CA9CA12
SCHEMBL10931081 0.80 LMNA (0.47) MEN1KMT2ATDP1L3MBTL1SRC
Phenyl Phosphordiamidate SCHEMBL28438502 0.80 L3MBTL1 (0.60) MEN1KMT2ACA1CA2CA9
SCHEMBL10936080 0.78 MEN1 (0.54) MEN1KMT2ACA1CA2CA9
SCHEMBL14128870 0.75 SRC (0.42) MEN1KMT2ACA1CA2CA9
SCHEMBL130697 0.75 INPPL1 (0.71) MEN1KMT2ACA1CA2SRC
SCHEMBL7764936 0.75 HCRTR1 (0.46) MEN1KMT2ACA1CA2CA9
SCHEMBL10935248 0.75 KMT2A (0.43) MEN1KMT2ACA1CA2CA9
SCHEMBL78015 0.73 SRC (0.54) MEN1KMT2ATDP1L3MBTL1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4518413-A Poly-phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1985-05-21 US claimed
US-4518413-A Poly-phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1985-05-21 US disclosed