Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13479734 | 0.87 | KDM4E (0.61) | TSHRRAB9AKDM4EHPGDKMT2A | |
| SCHEMBL11529647 | 0.86 | LMNA (0.50) | LMNAF2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL27402792 | 0.83 | LMNA (0.47) | LMNAF2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL28603710 | 0.83 | TSHR (0.48) | LMNAF2TSHRTDP1RAB9A | |
| SCHEMBL13992593 | 0.80 | MAPT (0.38) | LMNATSHRTDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6851360 | 0.79 | LMNA (0.56) | LMNAF2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL28813268 | 0.78 | KDM4E (0.46) | LMNAF2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL4526462 | 0.78 | HPGD (0.50) | TSHRTDP1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL8778288 | 0.78 | LMNA (0.54) | LMNAF2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL26630671 | 0.74 | LMNA (0.50) | LMNAF2TSHRTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056674-B1 | PROCESS FOR CROSS-LINKING POLYMERS | AKZO N.V. (NL) | 1985-05-29 | — | — | EP | disclosed |
| US-4409367-A | Process for cross-linking polymers | AKZONA INCORPORATED (US) | 1983-10-11 | — | — | US | disclosed |
| EP-0056674-A1 | Process for cross-linking polymers | AKZO N.V. (NL) | 1982-07-28 | — | — | EP | disclosed |