Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934660 | 0.94 | SIGMAR1 (0.59) | L3MBTL1SIGMAR1MEN1KMT2A | |
| SCHEMBL23070516 | 0.87 | SIGMAR1 (0.75) | L3MBTL1SIGMAR1 | |
| SCHEMBL9320464 | 0.85 | ATM (0.58) | L3MBTL1SIGMAR1MEN1KMT2A | |
| SCHEMBL7608570 | 0.84 | SIGMAR1 (0.77) | L3MBTL1SIGMAR1 | |
| SCHEMBL10395208 | 0.83 | SIGMAR1 (0.73) | L3MBTL1SIGMAR1MEN1KMT2A | |
| SCHEMBL25006483 | 0.82 | SIGMAR1 (0.81) | L3MBTL1SIGMAR1 | |
| SCHEMBL8135252 | 0.82 | SIGMAR1 (0.59) | L3MBTL1SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6378718 | 0.80 | L3MBTL1 (0.68) | L3MBTL1SIGMAR1MEN1KMT2A | |
| SCHEMBL9819972 | 0.80 | SIGMAR1 (0.85) | L3MBTL1SIGMAR1 | |
| SCHEMBL9819750 | 0.80 | SIGMAR1 (0.79) | L3MBTL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500452-A | NOT SUBJECT TO ENZYME DEACTIVATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4472304-A | CARCINOSTATIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |