Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | CASP2 | P42575 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | F13A1 | P00488 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939162 | 0.96 | ACE2 (0.56) | ACE2ALOX15CASP2CA12F13A1 | |
| SCHEMBL6506342 | 0.94 | ACE2 (0.54) | ACE2ALOX15CASP2CA12F13A1 | |
| SCHEMBL4361290 | 0.94 | ACE2 (0.54) | ACE2ALOX15CASP2CA12F13A1 | |
| SCHEMBL15295964 | 0.94 | ACE2 (0.54) | ACE2ALOX15CASP2CA12F13A1 | |
| SCHEMBL6510779 | 0.94 | ACE2 (0.54) | ACE2ALOX15CASP2CA12F13A1 | |
| SCHEMBL8310662 | 0.90 | ACE2 (0.64) | ACE2ALOX15CA12CA2CA4 | |
| SCHEMBL6825918 | 0.90 | ACE2 (0.64) | ACE2ALOX15CASP2CA12F13A1 | |
| SCHEMBL5705876 | 0.88 | ACE2 (0.68) | ACE2ALOX15CASP2CA12F13A1 | |
| SCHEMBL8307200 | 0.88 | ACE2 (0.61) | ACE2ALOX15CA12CA2CA4 | |
| SCHEMBL24773495 | 0.86 | ACE2 (0.72) | ACE2ALOX15CASP2CA12F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500452-A | NOT SUBJECT TO ENZYME DEACTIVATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4472304-A | CARCINOSTATIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |