Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936974 | 1.00 | LMNA (0.60) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10938018 | 0.92 | AR (0.53) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL9501753 | 0.91 | LMNA (0.61) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10938022 | 0.90 | LMNA (0.60) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10938025 | 0.90 | LMNA (0.60) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL6447018 | 0.89 | LMNA (0.65) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL6449571 | 0.89 | LMNA (0.65) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10938075 | 0.87 | LMNA (0.61) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10938070 | 0.87 | LMNA (0.61) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL11817969 | 0.86 | LMNA (0.62) | LMNAMAPTCYP19A1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58021699-A | — | — | None | — | — | JP | disclosed |
| JP-58021695-A | — | — | None | — | — | JP | disclosed |
| EP-0071178-B1 | ACYLOXYSTEROIDS AND PROCESS FOR PRODUCING SAME | MITSUBISHI KASEI CORPORATION (JP) | 1985-10-16 | — | — | EP | disclosed |
| US-4440689-A | Acyloxysteroids and process for producing same | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0071178-A1 | Acyloxysteroids and process for producing same | MITSUBISHI KASEI CORPORATION (JP) | 1983-02-09 | — | — | EP | disclosed |
| JP-S5821699-A | PREPARATION OF ALPHA-IODOKETONE | MITSUBISHI CHEM IND LTD | 1983-02-08 | — | — | JP | disclosed |
| JP-S5821695-A | PREPARATION OF DIIODOKETONE | MITSUBISHI CHEM IND LTD | 1983-02-08 | — | — | JP | disclosed |