Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938025 | 0.91 | LMNA (0.60) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10936974 | 0.91 | LMNA (0.60) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10938022 | 0.91 | LMNA (0.60) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10936967 | 0.91 | LMNA (0.60) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL6449571 | 0.90 | LMNA (0.65) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL6447018 | 0.90 | LMNA (0.65) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL11822457 | 0.90 | LMNA (0.58) | LMNAMAPTCYP19A1CYP3A4PGR | |
| SCHEMBL5493606 | 0.87 | LMNA (0.56) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL11817969 | 0.87 | LMNA (0.62) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10938075 | 0.86 | LMNA (0.61) | LMNAMAPTCYP19A1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256095-B1 | ANTI-INFLAMMATORY CARBOXY PREGNANE DERIVATIVES | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 1993-05-19 | — | — | EP | disclosed |
| EP-0256095-A4 | ANTI-INFLAMMATORY CARBOXY PREGNANE DERIVATIVES. | UNIV FLORIDA AGRICULT MECH (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0256095-A1 | ANTI-INFLAMMATORY CARBOXY PREGNANE DERIVATIVES. | UNIV FLORIDA AGRICULT MECH (US) | 1988-02-24 | — | — | EP | disclosed |
| WO-1987005028-A1 | ANTI-INFLAMMATORY CARBOXY PREGNANE DERIVATIVES | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 1987-08-27 | — | — | WO | disclosed |