Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618200 | 1.00 | LMNA (0.54) | LMNAKMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL10618206 | 1.00 | LMNA (0.54) | LMNAKMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL10938360 | 0.92 | LMNA (0.59) | LMNAKMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL10617277 | 0.92 | LMNA (0.59) | LMNAKMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL10617287 | 0.92 | LMNA (0.59) | LMNAKMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL10618189 | 0.88 | LMNA (0.55) | LMNAKMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL10618179 | 0.88 | LMNA (0.55) | LMNAKMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL11391188 | 0.88 | LMNA (0.54) | LMNAKMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL11391185 | 0.88 | LMNA (0.54) | LMNAKMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL10618215 | 0.84 | LMNA (0.60) | LMNAKMT2ATSHRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4547567-A | ANTICARCINOGENIC, ANTITUMOR AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-10-15 | — | — | US | disclosed |
| US-4252970-A | MULTISTEP PROCESS, ONE STEP IS DESULFONATION OF 6-SULFONYLNEAMINES TO FORM 5,6-DIDEOXY-5-OXONEAMINES | THE UPJOHN COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4232148-A | ANTIBACTERIAL | THE UPJOHN COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4169197-A | ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4038478-A | ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-3996205-A | BACTERICIDES | THE UPJOHN COMPANY (US) | 1976-12-07 | — | — | US | disclosed |
| US-3984393-A | BACTERICIDES | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |