SCHEMBL10937553

SCHEMBL10937553

CCC(N)(CC)NC(=O)C(=O)NC(N)(CC)CC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4828403 0.84 TDP1 (0.35) ALDH1A1
SCHEMBL5394315 0.81 MEN1 (0.37) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL9766460 0.74 ALDH1A1 (0.40) MEN1ALDH1A1THRBKMT2A
SCHEMBL3976745 0.69 ALDH1A1 (0.36) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL11128751 0.69 EPHX1 (0.47) MEN1ALDH1A1KMT2A
SCHEMBL20977597 0.67 PKM (0.32) THRB
SCHEMBL9868678 0.65 EPHX1 (0.40) MEN1ALDH1A1KMT2A
SCHEMBL9115954 0.65
SCHEMBL10572775 0.63
SCHEMBL5391004 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4542192-A Reactive hardenable polymer mixture and process for the preparation of hardened products therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-17 US disclosed
EP-0002284-B1 REACTIVE CURABLE POLYMER MIXTURE AND PROCESS FOR PREPARING CURED PRODUCTS THEREFROM HOECHST AKTIENGESELLSCHAFT (DE) 1984-02-01 EP disclosed
US-4208488-A POLYESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed
EP-0002284-A1 Reactive curable polymer mixture and process for preparing cured products therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1979-06-13 EP disclosed