Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.64 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | CDC25A | P30304 | 1/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | FABP3 | P05413 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720034 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT | |
| SCHEMBL29935531 | 0.94 | SMN1; SMN2 (0.63) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT | |
| SCHEMBL28625743 | 0.89 | ALDH1A1 (0.61) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT | |
| SCHEMBL10415337 | 0.89 | ALDH1A1 (0.61) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT | |
| SCHEMBL30555700 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT | |
| SCHEMBL29885925 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT | |
| SCHEMBL31577378 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT | |
| SCHEMBL30555917 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT | |
| SCHEMBL19821339 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT | |
| SCHEMBL29365200 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2NR5A2NR5A1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542219-A | ANTITUMOR, AGRICULTURAL FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-09-17 | — | — | US | disclosed |
| EP-0061872-B1 | ETHYLENEGLYCOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-08-07 | — | — | EP | disclosed |
| EP-0061872-A1 | Ethyleneglycol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-10-06 | — | — | EP | disclosed |