Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163326 | 0.88 | KMT2A (0.46) | KMT2ATSHRPOLBPIK3CDTHRB | |
| SCHEMBL161624 | 0.85 | TSHR (0.44) | KMT2ATSHRPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL31404679 | 0.84 | TSHR (0.46) | KMT2ATSHRPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL28785139 | 0.83 | TSHR (0.49) | KMT2ATSHRPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL17104459 | 0.83 | TSHR (0.49) | KMT2ATSHRPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL19146571 | 0.83 | TSHR (0.49) | KMT2ATSHRPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL11734811 | 0.83 | THRB (0.46) | KMT2ATSHRPOLBPIK3CDTHRB | |
| SCHEMBL11890775 | 0.83 | KMT2A (0.42) | KMT2ATSHRPOLBPIK3CDTHRB | |
| SCHEMBL12515375 | 0.82 | KMT2A (0.40) | KMT2ATSHRPOLBPIK3CDTHRB | |
| SCHEMBL4906332 | 0.82 | TSHR (0.45) | KMT2ATSHRPIK3CDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344090-B2 | PDMS-PVP block copolymers | DSM IP ASSETS B.V. (NL) | 2013-01-01 | — | — | US | disclosed |
| US-8153728-B2 | PDMS-PVP block copolymers | DSM IP ASSETS B.V. (NL) | 2012-04-10 | — | — | US | disclosed |
| US-20120083573-A1 | NOVEL PDMS-PVP BLOCK COPOLYMERS | PARAKKA JAMES (US) | 2012-04-05 | — | — | US | disclosed |
| US-20100099829-A1 | NOVEL PDMS-PVP BLOCK COPOLYMERS | THE POLYMER TECHNOLOGY GROUP INCORPORATED (US) | 2010-04-22 | — | — | US | disclosed |