Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12656022 | 0.94 | KMT2A (0.42) | TSHRPIK3CDKMT2AATMALDH1A1 | |
| SCHEMBL16389265 | 0.85 | PIK3CD (0.43) | TSHRPIK3CDKMT2AALDH1A1LMNA | |
| SCHEMBL163326 | 0.84 | KMT2A (0.46) | TSHRPIK3CDKMT2AALDH1A1 | |
| SCHEMBL8069623 | 0.83 | TSHR (0.50) | TSHRPIK3CDKMT2AHTTALDH1A1 | |
| SCHEMBL29144401 | 0.83 | KMT2A (0.53) | TSHRPIK3CDKMT2AHTTALDH1A1 | |
| SCHEMBL161624 | 0.82 | TSHR (0.44) | TSHRKMT2AHTTALDH1A1APEX1 | |
| SCHEMBL1093758 | 0.82 | KMT2A (0.41) | TSHRPIK3CDKMT2AALDH1A1 | |
| SCHEMBL7978944 | 0.81 | KMT2A (0.40) | TSHRPIK3CDKMT2AHTTALDH1A1 | |
| SCHEMBL31404679 | 0.81 | TSHR (0.46) | TSHRKMT2AHTTALDH1A1APEX1 | |
| SCHEMBL11890775 | 0.80 | KMT2A (0.42) | TSHRPIK3CDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025045458-A1 | OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX | BAUSCH + LOMB IRELAND LIMITED (IE) | 2025-03-06 | — | — | WO | claimed |
| US-20250073018-A1 | OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2025-03-06 | — | — | US | claimed |
| US-9512325-B2 | Compositions comprising a reactive monomer and uses thereof | ISP INVESTMENTS LLC (US) | 2016-12-06 | — | — | US | claimed |
| US-20250145562-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC DEVICES | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2025-05-08 | — | — | US | disclosed |
| WO-2025045458-A1 | OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX | BAUSCH + LOMB IRELAND LIMITED (IE) | 2025-03-06 | — | — | WO | disclosed |
| US-20250073018-A1 | OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2025-03-06 | — | — | US | disclosed |
| US-9512325-B2 | Compositions comprising a reactive monomer and uses thereof | ISP INVESTMENTS LLC (US) | 2016-12-06 | — | — | US | disclosed |
| US-9512325-B2 | Compositions comprising a reactive monomer and uses thereof | ISP INVESTMENTS LLC (US) | 2016-12-06 | — | — | US | disclosed |
| US-8778575-B2 | Curable composition, color filter using the same and manufacturing method therefor, and solid image pickup element | FUJIFILM CORPORATION (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20130150481-A1 | COMPOSITIONS COMPRISING A REACTIVE MONOMER AND USES THEREOF | HERCULES LLC | 2013-06-13 | — | — | US | disclosed |
| US-20130150481-A1 | COMPOSITIONS COMPRISING A REACTIVE MONOMER AND USES THEREOF | HERCULES LLC | 2013-06-13 | — | — | US | disclosed |
| US-6465588-B1 | PARTICULARLY SUITABLE FOR FOLDABLE INTRAOCULAR LENS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-10-15 | — | — | US | disclosed |
| EP-0869138-B1 | NOVEL COPOLYMERS FORMED FROM THREE COMPONENTS AND INTRAOCULAR LENSES MADE THEREOF | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-6132462-A | HYDROXYALKYL (ALKYL)ACRYLATE; PYRROLIDONE-CONTAINING ACRYLIC ESTER, AMIDE, OR IMIDE; AND A LOWER ALKYL (ALKYL)ACRYLATE TERPOLYMER; FOLDABLE LENSE HAVING GIVEN REFRACTIVE INDEX, RECOVERY SPEED FROM FOLD STATE AND TENSILE STRENGTH | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-1026182-A1 | FOUR COMPONENT COPOLYMER AND THE OCULAR LENS MADE THEREOF | SANTEN PHARMACEUTICAL CO., LTD (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-5947274-A | Desiccating container for moisture-sensitive material | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-09-07 | — | — | US | disclosed |
| EP-0869138-A1 | NOVEL COPOLYMERS FORMED FROM THREE COMPONENTS AND INTRAOCULAR LENSES MADE THEREOF | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5294401-A | Blood gas exchange | TERUMO KABUSHIKI KAISHA (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0354959-B1 | MEMBRANE TYPE ARTIFICIAL LUNG AND PRODUCTION THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0354959-A1 | MEMBRANE TYPE ARTIFICIAL LUNG AND PRODUCTION THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1990-02-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145562-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC DEVICES | CRY1, NFXL1, ZYX | TSHR 3668/4885PIK3CD 4542/4885KMT2A 2325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.