Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938264 | 0.88 | CYP1A2 (0.47) | ALDH1A1MAPTPOLBMAPK1CYP1A2 | |
| SCHEMBL11032516 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBMAPK1CYP1A2 | |
| SCHEMBL38657948 | 0.82 | ALDH1A1 (0.74) | ALDH1A1MAPTPOLBCYP1A2SMN1; SMN2 | |
| SCHEMBL2634390 | 0.82 | ALDH1A1 (0.74) | ALDH1A1MAPTPOLBCYP1A2SMN1; SMN2 | |
| SCHEMBL11095358 | 0.79 | TDP1 (0.57) | ALDH1A1MAPTPOLBCYP1A2SMN1; SMN2 | |
| SCHEMBL10936519 | 0.79 | MAPK1 (0.42) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10773281 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBCYP1A2SMN1; SMN2 | |
| SCHEMBL10779620 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBCYP1A2SMN1; SMN2 | |
| SCHEMBL10954210 | 0.77 | MAPT (0.40) | ALDH1A1MAPTPOLBMAPK1CYP1A2 | |
| SCHEMBL11093340 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTPOLBCYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4511729-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |
| US-4476315-A | NITROARYLACETIC ACID ESTERS FROM NITROAROMATIC COMPOUNDS | ETHYL CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |