Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937718 | 0.88 | ALDH1A1 (0.56) | CYP1A2MAPTPOLBALDH1A1TSHR | |
| SCHEMBL11032516 | 0.82 | ALDH1A1 (0.41) | CYP1A2PTGS1MAPTPOLBALDH1A1 | |
| SCHEMBL2431833 | 0.81 | CYP1A2 (0.63) | CYP1A2MAPTALDH1A1TSHRTDP1 | |
| SCHEMBL2431836 | 0.81 | CYP1A2 (0.63) | CYP1A2MAPTALDH1A1TSHRTDP1 | |
| SCHEMBL10954210 | 0.80 | MAPT (0.40) | CYP1A2MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10717343 | 0.80 | TSHR (0.50) | CYP1A2MAPTPOLBALDH1A1TSHR | |
| SCHEMBL11649655 | 0.79 | HSPB1 (0.50) | MAPTPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10937484 | 0.77 | PTGS1 (0.51) | PTGS1MEN1KMT2ACYP2D6L3MBTL1 | |
| SCHEMBL10685950 | 0.76 | CYP1A2 (0.49) | CYP1A2MAPTPOLBALDH1A1TSHR | |
| SCHEMBL10774171 | 0.76 | CYP1A2 (0.49) | CYP1A2MAPTPOLBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4511729-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1985-04-16 | — | — | US | claimed |
| US-4502998-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1985-03-05 | — | — | US | claimed |
| US-4511729-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |
| US-4502998-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1985-03-05 | — | — | US | disclosed |