Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10938133 | 0.93 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTMAPK1JMJD6 | |
| Hydrochloric Acid SCHEMBL10941122 | 0.91 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTSLC11A2RAB9A | |
| Hydrochloric Acid SCHEMBL10936444 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL10938104 | 0.89 | S1PR3 (0.47) | ALDH1A1KDM4EMAPTTSHRRAB9A | |
| SCHEMBL10938253 | 0.78 | RAB9A (0.48) | ALDH1A1MAPTJMJD6F2RL3RAB9A | |
| SCHEMBL4676096 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTSLC11A2RAB9A | |
| SCHEMBL10940170 | 0.76 | SMN1; SMN2 (0.47) | ALDH1A1MAPTTSHRJMJD6RAB9A | |
| SCHEMBL4676931 | 0.75 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTSLC11A2RAB9A | |
| SCHEMBL10940219 | 0.73 | EGFR (0.48) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL16827699 | 0.72 | CREBBP (0.51) | ALDH1A1KDM4EMAPTSLC11A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4511575-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4511576-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |