Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619852 | 0.81 | CASP6 (0.51) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7408400 | 0.81 | CYP3A4 (0.55) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL6610343 | 0.81 | MEN1 (0.42) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL12490166 | 0.77 | MAPT (0.45) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL27668818 | 0.77 | CYP3A4 (0.50) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10902960 | 0.73 | AGTR1 (0.47) | CYP3A4ALDH1A1MEN1KMT2APIM1 | |
| SCHEMBL28270294 | 0.73 | CYP19A1 (0.50) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29450703 | 0.72 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL57759 | 0.72 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL15159218 | 0.72 | NQO2 (0.43) | CYP3A4TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582947-A | Nucleophilic displacement process for preparing 2,6-dihydrocarbonyl-4-(nitroaryl)phenol | ETHYL CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |