Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942691 | 0.92 | SMN1; SMN2 (0.40) | MAPK14NPC1ALDH1A1GAARAB9A | |
| SCHEMBL9680435 | 0.91 | SRD5A1 (0.48) | MAPK14NPC1ALDH1A1GAARAB9A | |
| SCHEMBL10945183 | 0.89 | CES1 (0.44) | MAPK14NPC1ALDH1A1GAARAB9A | |
| SCHEMBL9681137 | 0.88 | ALDH1A1 (0.50) | MAPK14ALDH1A1SMN1; SMN2 | |
| SCHEMBL10943467 | 0.87 | ALDH1A1 (0.41) | MAPK14NPC1ALDH1A1GAARAB9A | |
| SCHEMBL10943943 | 0.85 | ALDH1A1 (0.54) | NPC1ALDH1A1GAARAB9AL3MBTL1 | |
| SCHEMBL10948642 | 0.85 | ALDH1A1 (0.54) | NPC1ALDH1A1GAARAB9AL3MBTL1 | |
| SCHEMBL10941113 | 0.84 | ALDH1A1 (0.38) | NPC1ALDH1A1GAARAB9AL3MBTL1 | |
| SCHEMBL10944726 | 0.84 | ALDH1A1 (0.52) | NPC1ALDH1A1GAARAB9AL3MBTL1 | |
| SCHEMBL10947824 | 0.84 | L3MBTL1 (0.45) | NPC1ALDH1A1GAARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |