Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940216 | 1.00 | CYP19A1 (0.62) | CYP19A1CYP3A4LMNAMEN1ALOX15 | |
| SCHEMBL11425160 | 0.90 | CYP19A1 (0.62) | CYP19A1CYP3A4LMNAMEN1ALOX15 | |
| SCHEMBL11425163 | 0.90 | CYP19A1 (0.62) | CYP19A1CYP3A4LMNAMEN1ALOX15 | |
| SCHEMBL3102365 | 0.89 | CYP3A4 (0.59) | CYP19A1CYP3A4LMNAMEN1ALOX15 | |
| SCHEMBL3102374 | 0.89 | CYP3A4 (0.59) | CYP19A1CYP3A4LMNAMEN1ALOX15 | |
| SCHEMBL11230035 | 0.80 | CYP19A1 (0.72) | CYP19A1CYP3A4LMNAMEN1MAPK1 | |
| SCHEMBL11640618 | 0.80 | CYP19A1 (0.72) | CYP19A1CYP3A4LMNAMEN1MAPK1 | |
| SCHEMBL11230040 | 0.80 | CYP19A1 (0.72) | CYP19A1CYP3A4LMNAMEN1MAPK1 | |
| SCHEMBL11821082 | 0.80 | SHBG (0.68) | CYP19A1CYP3A4LMNAMEN1ALOX15 | |
| SCHEMBL11430632 | 0.80 | CYP3A4 (0.58) | CYP19A1CYP3A4LMNAMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546098-A | ANTIESTROGENS; HORMONE INHIBITORS | THE ROCKEFELLER UNIVERSITY (US) | 1985-10-08 | — | — | US | disclosed |