SCHEMBL3102374

SCHEMBL3102374

CC(=O)OC1CC[C@H]2[C@@H]3CCC4=C(O)C(=O)CC[C@]4(C)[C@@H]3CC[C@]12C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.59
TSHR P16473 2/20 0.59
THPO P40225 1/20 0.59
HIF1A Q16665 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
SHBG P04278 1/20 0.54
CYP19A1 P11511 8/20 0.53
CYP2C19 P33261 2/20 0.52
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
NR1I2 O75469 1/20 0.51
NR3C1 P04150 1/20 0.51
CYP17A1 P05093 1/20 0.51
PGR P06401 1/20 0.51
AR P10275 1/20 0.51
CYP2C9 P11712 1/20 0.51
OPRK1 P41145 1/20 0.51
SRD5A2 P31213 2/20 0.50
MEN1 O00255 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3102365 1.00 CYP3A4 (0.59) CYP3A4TSHRTHPOHIF1ATDP1
SCHEMBL11821082 0.90 SHBG (0.68) CYP3A4TSHRTHPOHIF1ATDP1
SCHEMBL10940211 0.89 CYP19A1 (0.62) CYP3A4TSHRTHPOHIF1ATDP1
SCHEMBL10940216 0.89 CYP19A1 (0.62) CYP3A4TSHRTHPOHIF1ATDP1
SCHEMBL2251175 0.89 SRD5A2 (0.61) CYP3A4TSHRTHPOHIF1ATDP1
SCHEMBL216171 0.89 SRD5A2 (0.61) CYP3A4TSHRTHPOHIF1ATDP1
SCHEMBL8340076 0.85 SHBG (0.48) CYP3A4TSHRTHPOHIF1ATDP1
SCHEMBL8340073 0.85 SHBG (0.48) CYP3A4TSHRTHPOHIF1ATDP1
SCHEMBL11231672 0.84 CYP3A4 (0.52) CYP3A4TSHRTHPOHIF1ATDP1
SCHEMBL2540247 0.82 CYP3A4 (0.63) CYP3A4TSHRTHPOHIF1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10265328-B2 C-19 steroids for specific therapeutic uses PROCIMA GMBH (DE) 2019-04-23 US disclosed
EP-2949361-B1 C-19 STEROIDS FOR TREATING CELLULITE ATHENION AG (CH) 2017-03-22 EP disclosed
EP-2060261-B1 C-19 steroids for cosmetic uses ATHENION AG (CH) 2016-03-09 EP disclosed
EP-2949361-A1 C-19 steroids for treating cellulite Curadis GmbH (DE) 2015-12-02 EP disclosed
EP-2500062-B1 C-19 steroids for specific therapeutic uses CURADIS GMBH (DE) 2015-08-12 EP disclosed
EP-2564900-B1 C-19 steroids for therapeutic uses CURADIS GMBH (DE) 2015-04-22 EP disclosed
EP-2060300-B1 C-19 steroids for therapeutic uses CURADIS GMBH (DE) 2015-04-15 EP disclosed
EP-2564900-A1 C-19 steroids for therapeutic uses Procima GmbH (DE) 2013-03-06 EP disclosed
EP-2500062-A2 C-19 steroids for specific therapeutic uses Procima GmbH (DE) 2012-09-19 EP disclosed
US-8258123-B2 C-19 steroids for cosmetic and further uses ERLACOS GMBH (DE) 2012-09-04 US disclosed
EP-2260903-A1 C-19 steroids for therapeutic uses Procima GmbH (DE) 2010-12-15 EP disclosed
US-20100256102-A1 C-19 STEROIDS FOR COSMETIC AND FURTHER USES ERLACOS GMBH (DE) 2010-10-07 US disclosed
WO-2009062683-A1 C-19 STEROIDS FOR THERAPEUTIC USES ERLACOS GMBH (DE) 2009-05-22 WO disclosed
EP-2060300-A1 C-19 steroids for therapeutic uses ErlaCos GmbH (DE) 2009-05-20 EP disclosed
EP-2060261-A1 C-19 steroids for cosmetic and further uses ErlaCos GmbH (DE) 2009-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10265328-B2 C-19 steroids for specific therapeutic uses AR, CYP17A1, SHBG CYP3A4 113/4885TSHR 743/4885THPO 4776/4885
US-20100256102-A1 C-19 STEROIDS FOR COSMETIC AND FURTHER USES HSD17B7, HSD17B13, HSD3B2 CYP3A4 78/4885TSHR 215/4885THPO 4877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.