Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | CTSG | P08311 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | CMA1 | P23946 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937042 | 0.88 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10940306 | 0.88 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10946092 | 0.88 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL11129254 | 0.88 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10944558 | 0.88 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10942611 | 0.88 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10941734 | 0.87 | ALDH1A1 (0.38) | ALDH1A1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9743488 | 0.86 | GLS2 (0.41) | ALDH1A1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10941156 | 0.84 | KCNN4 (0.40) | — | |
| SCHEMBL10796999 | 0.84 | PLA2G2A (0.43) | ALDH1A1PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070433-B1 | PHOSPHOLIPID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| US-4493832-A | HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0070433-A1 | Phospholipid derivatives, processes for preparation thereof and pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-26 | — | — | EP | disclosed |