Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939749 | 0.81 | TSHR (0.38) | TSHRALDH1A1PTPN1HTTCYP2D6 | |
| SCHEMBL28031020 | 0.74 | CYP1A2 (0.50) | TSHRALDH1A1PTPN1CYP2D6MAPK1 | |
| SCHEMBL10939639 | 0.72 | CYP2C19 (0.44) | TSHRALDH1A1PTPN1HTTCYP2D6 | |
| SCHEMBL27880149 | 0.71 | ALDH1A1 (0.38) | TSHRALDH1A1PTPN1HTTCA1 | |
| SCHEMBL6991557 | 0.71 | CYP2C9 (0.44) | TSHRALDH1A1HTTCYP2D6SMN1; SMN2 | |
| SCHEMBL8009556 | 0.71 | ALDH1A1 (0.42) | TSHRALDH1A1PTPN1HTTCYP2D6 | |
| SCHEMBL440368 | 0.70 | KIF11 (0.41) | TSHRALDH1A1HTTCYP2C19KMT2A | |
| SCHEMBL6544164 | 0.70 | ALDH1A1 (0.41) | TSHRALDH1A1PTPN1HTTCYP2C19 | |
| SCHEMBL28460943 | 0.69 | PTPN1 (0.35) | TSHRALDH1A1PTPN1CYP2D6MAPK1 | |
| SCHEMBL27565434 | 0.69 | ALDH1A1 (0.46) | TSHRALDH1A1PTPN1HTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4543166-A | NICKEL, COBALT, ELECTRODEPOSITION, BRIGHTENERS, PUCTILITY, SULFONATES | OMI INTERNATIONAL CORPORATION (US) | 1985-09-24 | — | — | US | disclosed |
| US-4252619-A | Brightener for zinc electroplating solutions and process | OXY METAL INDUSTRIES CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |