Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10613566 | 0.86 | PPOX (0.65) | PPOXARKMT2ATSHRL3MBTL1 | |
| SCHEMBL10935874 | 0.82 | AR (0.45) | PPOXARKMT2AALDH1A1MAPT | |
| SCHEMBL10939313 | 0.77 | PPOX (0.54) | PPOXARPOLBTHRB | |
| SCHEMBL13879455 | 0.77 | KDM4E (0.56) | ARKMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8685948 | 0.76 | PPOX (0.53) | PPOXARKMT2APOLB | |
| SCHEMBL11554852 | 0.76 | KMT2A (0.51) | PPOXARKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL10611058 | 0.76 | PPOX (0.63) | PPOXKMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL10938117 | 0.75 | PPOX (0.51) | PPOXARSMN1; SMN2HTR1A | |
| SCHEMBL10440318 | 0.75 | AR (0.45) | PPOXARKMT2ATSHRALDH1A1 | |
| SCHEMBL1514017 | 0.75 | AR (0.43) | ARKMT2ATSHRL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070389-B1 | 2-(2-FLUORO-4-HALO-5-SUBSTITUTED PHENYL) HYDANTOINS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-10-02 | — | — | EP | claimed |