Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPOX | P50336 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10935874 | 0.85 | AR (0.45) | ARKMT2ASMN1; SMN2ALDH1A1PPOX | |
| SCHEMBL9664391 | 0.85 | AR (0.45) | ARKMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9382971 | 0.82 | AR (0.42) | ARSMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10463025 | 0.80 | AR (0.40) | ARKMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10440314 | 0.78 | AR (0.43) | ARKMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10440334 | 0.77 | PPOX (0.43) | ARKMT2ASMN1; SMN2ALDH1A1PPOX | |
| SCHEMBL10823806 | 0.77 | HPGD (0.42) | ARPOLBTSHRSMN1; SMN2PPOX | |
| SCHEMBL10440441 | 0.77 | PPOX (0.41) | ARKMT2ASMN1; SMN2PPOX | |
| SCHEMBL9389966 | 0.76 | AR (0.45) | ARKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10940936 | 0.75 | PPOX (0.47) | ARKMT2APOLBTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363585-A1 | N-aryl nitrogen heterocycles | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |