SCHEMBL10940945

SCHEMBL10940945

CCCCCCCCCCCCOCC(CO)OC(=O)OCC

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.51
PRKCA P17252 5/20 0.51
PRKCE Q02156 2/20 0.51
PRKCQ Q04759 2/20 0.51
PRKCD Q05655 2/20 0.51
PLA2G2C Q5R387 2/20 0.47
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
LPAR1 Q92633 2/20 0.43
LPAR3 Q9UBY5 2/20 0.43
AKT1 P31749 2/20 0.43
AKT2 P31751 2/20 0.43
AKT3 Q9Y243 2/20 0.43
PIK3R1 P27986 1/20 0.43
PIK3CA P42336 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10941828 0.91 USP2 (0.51) USP2PRKCAPRKCEPRKCQPRKCD
SCHEMBL10943913 0.91 USP2 (0.56) USP2PRKCAPRKCEPRKCQPRKCD
SCHEMBL10939817 0.88 PRKCA (0.49) USP2PRKCAPRKCEPRKCQPRKCD
SCHEMBL10941567 0.87 USP2 (0.54) USP2PRKCAPRKCEPRKCQPRKCD
SCHEMBL10940410 0.87 USP2 (0.54) USP2PRKCAPRKCEPRKCQPRKCD
SCHEMBL10942036 0.87 USP2 (0.54) USP2PRKCAPRKCEPRKCQPRKCD
SCHEMBL10938399 0.87 USP2 (0.54) USP2PRKCAPRKCEPRKCQPRKCD
SCHEMBL9575676 0.87 USP2 (0.54) USP2PRKCAPRKCEPRKCQPRKCD
SCHEMBL11128122 0.87 USP2 (0.54) USP2PRKCAPRKCEPRKCQPRKCD
SCHEMBL10938100 0.87 USP2 (0.54) USP2PRKCAPRKCEPRKCQPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0070433-B1 PHOSPHOLIPID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION OF THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-11-27 EP disclosed
US-4493832-A HYPOTENSIVE AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-01-15 US disclosed
EP-0070433-A1 Phospholipid derivatives, processes for preparation thereof and pharmaceutical composition of the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-01-26 EP disclosed