SCHEMBL10941014

SCHEMBL10941014

c1ccc2c(c1)Cc1ccccc1N2c1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPT P10636 2/20 0.46
PKM P14618 1/20 0.46
HTR1A P08908 7/20 0.46
HTR7 P34969 5/20 0.46
TSHR P16473 2/20 0.46
HTR3E A5X5Y0 1/20 0.46
HTR3B O95264 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
NCF1 P14598 1/20 0.46
NFKB1 P19838 1/20 0.46
HTR1D P28221 1/20 0.46
HTR1B P28222 1/20 0.46
HTR2A P28223 1/20 0.46
MTOR P42345 1/20 0.46
HTR3A P46098 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7846622 0.85 HPGD (0.59) POLBALDH1A1HPGDHSD17B10MAPT
SCHEMBL6024042 0.83 HPGD (0.40) POLBALDH1A1HPGDHSD17B10MAPT
SCHEMBL30285929 0.83 POLB (0.63) POLBALDH1A1HPGDHSD17B10MAPT
SCHEMBL18770820 0.83 POLB (0.63) POLBALDH1A1HPGDHSD17B10MAPT
SCHEMBL8990319 0.83 POLB (0.63) POLBALDH1A1HPGDHSD17B10MAPT
SCHEMBL6024354 0.80 CYP3A4 (0.47) POLBALDH1A1HPGDHSD17B10MAPT
SCHEMBL13244804 0.80 TSHR (0.38) POLBALDH1A1HPGDHSD17B10MAPT
SCHEMBL13428341 0.80 POLB (0.41) POLBALDH1A1HPGDHSD17B10MAPT
SCHEMBL24463911 0.80 POLB (0.41) POLBALDH1A1HPGDHSD17B10MAPT
SCHEMBL10305939 0.78 POLB (0.35) POLBALDH1A1HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017070560-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2017-04-27 WO disclosed
EP-0035530-B1 IMAGEABLE, COMPOSITE DRY-TRANSFER SHEET MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-23 EP disclosed
EP-0035530-A4 IMAGEABLE, COMPOSITE DRY-TRANSFER SHEET. MINNESOTA MINING & MFG (US) 1982-07-30 EP disclosed
US-4291114-A COMPRISING A PHOTOPOLYMERIZABLE LAYER OF A MONOMER AND A CATIONIC PROMOTER ON AN OLEOPHILIC SURFACE OF A COVERING MINNESOTA MINING AND MANUFACTURING CO. (US) 1981-09-22 US disclosed
EP-0035530-A1 IMAGEABLE, COMPOSITE DRY-TRANSFER SHEET. MINNESOTA MINING & MFG (US) 1981-09-16 EP disclosed
WO-1981000627-A1 IMAGEABLE,COMPOSITE DRY-TRANSFER SHEET MINNESOTA MINING & MFG (US) 1981-03-05 WO disclosed