SCHEMBL18770820

SCHEMBL18770820

c1ccc2c(c1)N(c1cccc3ccccc13)c1ccccc1N2c1cccc2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.63
ELANE P08246 1/20 0.53
ALDH1A1 P00352 7/20 0.50
HSD17B10 Q99714 4/20 0.50
HPGD P15428 3/20 0.50
TSHR P16473 3/20 0.50
CYP1A2 P05177 3/20 0.50
MAPT P10636 2/20 0.50
MAPK1 P28482 2/20 0.50
PKM P14618 1/20 0.50
NPC1 O15118 1/20 0.50
HTR3E A5X5Y0 1/20 0.50
HTR3B O95264 1/20 0.50
HTR1A P08908 1/20 0.50
CYP2D6 P10635 1/20 0.50
NCF1 P14598 1/20 0.50
NFKB1 P19838 1/20 0.50
HTR1D P28221 1/20 0.50
HTR1B P28222 1/20 0.50
HTR2A P28223 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30285929 1.00 POLB (0.63) POLBELANEALDH1A1HSD17B10HPGD
SCHEMBL8990319 1.00 POLB (0.63) POLBELANEALDH1A1HSD17B10HPGD
SCHEMBL19343021 0.92 POLB (0.61) POLBELANEALDH1A1HSD17B10HPGD
SCHEMBL13296020 0.89 POLB (0.53) POLBELANEALDH1A1HSD17B10HPGD
SCHEMBL17794545 0.86 POLB (0.55) POLBELANEALDH1A1HSD17B10HPGD
SCHEMBL24434125 0.84 POLB (0.53) POLBELANEALDH1A1HSD17B10HPGD
SCHEMBL13425438 0.84 POLB (0.49) POLBELANEALDH1A1HSD17B10HPGD
SCHEMBL10941014 0.83 POLB (0.52) POLBELANEALDH1A1HSD17B10HPGD
SCHEMBL30867065 0.83 POLB (0.52) POLBELANEALDH1A1HSD17B10HPGD
SCHEMBL30286094 0.83 BCHE (0.54) POLBELANEALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106893015-B Method for preparing polymer by photoinduced organic catalysis under microscale 南京工业大学 2019-09-20 CN claimed
CN-106893039-B Method for modifying photo-induced organic catalytic polymer 南京工业大学 2019-04-12 CN claimed
US-11345771-B2 Compositions and methods of promoting organic photocatalysis THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2022-05-31 US disclosed
US-11345771-B2 Compositions and methods of promoting organic photocatalysis THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2022-05-31 US disclosed
US-10975171-B2 Compositions and methods of promoting organic photocatalysis THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-04-13 US disclosed
US-10975171-B2 Compositions and methods of promoting organic photocatalysis THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-04-13 US disclosed
CN-106893015-B Method for preparing polymer by photoinduced organic catalysis under microscale 南京工业大学 2019-09-20 CN disclosed
CN-106893039-B Method for modifying photo-induced organic catalytic polymer 南京工业大学 2019-04-12 CN disclosed
US-20180237550-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS CHARGEPOINT INC. 2018-08-23 US disclosed
CN-106893039-A Method for modifying photo-induced organic catalytic polymer 南京工业大学 2017-06-27 CN disclosed
CN-106893015-A Method for preparing polymer by photoinduced organic catalysis under microscale 南京工业大学 2017-06-27 CN disclosed
WO-2017070560-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2017-04-27 WO disclosed
WO-2017070560-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2017-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345771-B2 Compositions and methods of promoting organic photocatalysis TYR, ALKBH2, CYBB POLB 129/4885ELANE 2119/4885ALDH1A1 1151/4885
US-20180237550-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS TYR, ALKBH2, CYBB POLB 129/4885ELANE 2119/4885ALDH1A1 1151/4885
US-10975171-B2 Compositions and methods of promoting organic photocatalysis TYR, ALKBH2, CYBB POLB 129/4885ELANE 2119/4885ALDH1A1 1151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.