SCHEMBL1094149

SCHEMBL1094149

OC(OC(O)c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
MAPK1 P28482 1/20 0.46
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
TSHR P16473 1/20 0.44
KDM4E B2RXH2 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ADRA2A P08913 1/20 0.42
ADRA2C P18825 1/20 0.42
HIF1A Q16665 1/20 0.42
CYP2D6 P10635 1/20 0.42
SRC P12931 1/20 0.42
DPP4 P27487 2/20 0.41
F2 P00734 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18954122 0.83 LMNA (0.45) LMNAMAPK1TSHRKDM4EADRA2A
SCHEMBL5879080 0.82 LMNA (0.46) LMNAMAPK1TSHRKDM4EL3MBTL1
SCHEMBL3557022 0.81 CYP2D6 (0.54) LMNAMAPK1CES2CES1TSHR
SCHEMBL13551473 0.81 CYP2D6 (0.54) LMNAMAPK1CES2CES1TSHR
SCHEMBL10742661 0.81 ADRA2C (0.54) LMNATSHRKDM4EADRA2AADRA2C
SCHEMBL16920295 0.78 KMT2A (0.46) LMNAMAPK1TSHRKDM4EADRA2A
SCHEMBL16920301 0.78 KMT2A (0.46) LMNAMAPK1TSHRKDM4EADRA2A
SCHEMBL8923168 0.78 LMNA (0.44) LMNAMAPK1CES2CES1TSHR
SCHEMBL619133 0.78 KMT2A (0.46) LMNAMAPK1TSHRKDM4EADRA2A
SCHEMBL12919553 0.78 TSHR (0.52) LMNAMAPK1TSHRKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929650-B Synthesis method of 2, 3-unsaturated sugar-carbon glycoside compounds 三峡大学 2023-08-01 CN claimed
US-5139823-A Coating internal surfaces of reactors with polyhydroxy benzyl or polyhydroxy benzyl ether polymers INVESTIGACION Y DESARROLLO C.A. (VE) 1992-08-18 US claimed
US-4692555-A Preparation of diphenolics ETHYL CORPORATION (US) 1987-09-08 US claimed
US-4259534-A Method for the production of 2,4,6-tri(3,5-ditertiary butyl-4-hydroxybenzyl) mesitylene GURVICH YAKOV A 1981-03-31 US claimed
JP-63126815-A None JP disclosed
JP-10316637-A None JP disclosed
CN-119997386-A Preparation process of ultralow dielectric constant circuit board 开平依利安达电子第五有限公司 2025-05-13 CN disclosed
WO-2023143374-A1 LIGAND, METHOD FOR PREPARING SAME, AND USE THEREOF 成都凌泰氪生物技术有限公司 2023-08-03 WO disclosed
CN-113929650-B Synthesis method of 2, 3-unsaturated sugar-carbon glycoside compounds 三峡大学 2023-08-01 CN disclosed
CN-114728999-A Oligonucleotides containing nucleotide analogs 赛诺菲 2022-07-08 CN disclosed
US-8153828-B2 Optical molecular sensors for cytochrome P450 activity Life Technologies Corporation (US) 2012-04-10 US disclosed
US-20100105095-A1 Optical Molecular Sensors for Cytochrome P450 Activity Life Technologies Corporation (US) 2010-04-29 US disclosed
CN-1267277-A Method for etherifying benzyl alcohol, resulting products and applications RHODIA CHIMIE SA (FR) 2000-09-20 CN disclosed
WO-2000035900-A1 OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY AURORA BIOSCIENCES CORPORATION (US) 2000-06-22 WO disclosed
JP-H10316637-A DIHYDROXYDIAMINO COMPOUND AND ITS PRODUCTION MITSUI CHEM INC 1998-12-02 JP disclosed
US-5139823-A Coating internal surfaces of reactors with polyhydroxy benzyl or polyhydroxy benzyl ether polymers INVESTIGACION Y DESARROLLO C.A. (VE) 1992-08-18 US disclosed
EP-0194601-B1 METAL-MODIFIED PHENOLIC RESINS AND METHODS OF PREPARATION OCCIDENTAL CHEMICAL CORPORATION (US) 1989-09-06 EP disclosed
JP-S63126815-A SHAMPOO COMPOSITION LION CORP 1988-05-30 JP disclosed
EP-0194601-A1 Metal-Modified phenolic resins and methods of preparation OCCIDENTAL CHEMICAL CORPORATION (US) 1986-09-17 EP disclosed
US-4612254-A Aromatic carboxylic acid and metal-modified phenolic resins and methods of preparation OCCIDENTAL CHEMICAL CORPORATION (US) 1986-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105095-A1 Optical Molecular Sensors for Cytochrome P450 Activity CYP2J2, CYP1A2, CYP2B6 LMNA 2336/4885MAPK1 3474/4885CES2 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.