Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942439 | 0.87 | NR1H3 (0.58) | NR1H3NR1H2ALDH1A1LMNAUSP2 | |
| SCHEMBL10944048 | 0.79 | NR1H3 (0.52) | NR1H3NR1H2ALDH1A1LMNAHPGD | |
| SCHEMBL10940616 | 0.75 | ATM (0.44) | NR1H3NR1H2ALDH1A1LMNAHPGD | |
| SCHEMBL8304887 | 0.73 | HSD11B1 (0.55) | NR1H3NR1H2ALDH1A1LMNAMAPT | |
| SCHEMBL9831268 | 0.73 | HSD11B1 (0.54) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29411966 | 0.71 | KDM4E (0.56) | ALDH1A1LMNAMAPTHPGDPOLB | |
| SCHEMBL28493341 | 0.71 | KDM4E (0.56) | ALDH1A1LMNAMAPTHPGDPOLB | |
| SCHEMBL9831536 | 0.71 | HSD11B1 (0.55) | NR1H3ALDH1A1HSD17B10EGFRTUBB4A | |
| SCHEMBL9832147 | 0.71 | HSD11B1 (0.52) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9830317 | 0.71 | HSD11B1 (0.55) | EGFRTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036711-B1 | PESTICIDAL HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND THEIR USE | FBC LIMITED (GB) | 1985-12-04 | — | — | EP | disclosed |
| US-4414221-A | MITICIDES, INSECTICIDES, APHIDICIDES | FBC LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| EP-0036711-A2 | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use | FBC LIMITED (GB) | 1981-09-30 | — | — | EP | disclosed |