Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303627 | 0.90 | HSD11B1 (0.45) | HSD11B1NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL10939886 | 0.89 | HSD11B1 (0.46) | HSD11B1NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL6946561 | 0.86 | KDM4E (0.44) | HSD11B1NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL10941382 | 0.86 | HSD11B1 (0.50) | HSD11B1NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL9705543 | 0.85 | HSD11B1 (0.62) | HSD11B1 | |
| SCHEMBL9830823 | 0.85 | HSD11B1 (0.62) | HSD11B1ALDH1A1KDM4E | |
| SCHEMBL8876943 | 0.85 | CRHR1 (0.43) | HSD11B1NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL6951494 | 0.83 | DPP4 (0.42) | HSD11B1NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL8301501 | 0.83 | RAB9A (0.51) | HSD11B1NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL4611901 | 0.83 | HSD11B1 (0.56) | HSD11B1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036711-B1 | PESTICIDAL HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND THEIR USE | FBC LIMITED (GB) | 1985-12-04 | — | — | EP | claimed |
| US-4414221-A | MITICIDES, INSECTICIDES, APHIDICIDES | FBC LIMITED (GB) | 1983-11-08 | — | — | US | claimed |
| EP-0036711-A2 | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use | FBC LIMITED (GB) | 1981-09-30 | — | — | EP | claimed |
| EP-0648752-B1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5700824-A | Triazole derivatives, insecticide, acaricide and methods thereof | KUMIAI CHEMICAL INDUSTRIAL CO. LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5616594-A | Triazole derivatives, insecticide, acaricide and methods thereof | IHARA CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0572142-B1 | Novel 3,5-diphenyl substituted 1,2,4-triazoles and their use as insecticides and acaricides | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1996-07-31 | — | — | EP | disclosed |
| US-5482951-A | Triazole derivatives as well as insecticide and acaricide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0648752-A1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5318959-A | A new miticides diaryl alkyl 1,2,4-triazoles | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0572142-A2 | Novel 3,5-diphenyl substituted 1,2,4-triazoles and their use as insecticides and acaricides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |
| EP-0036711-B1 | PESTICIDAL HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND THEIR USE | FBC LIMITED (GB) | 1985-12-04 | — | — | EP | disclosed |
| US-4414221-A | MITICIDES, INSECTICIDES, APHIDICIDES | FBC LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| EP-0036711-A2 | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use | FBC LIMITED (GB) | 1981-09-30 | — | — | EP | disclosed |