Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745543 | 0.94 | ALDH1A1 (0.72) | ALDH1A1HDAC8HDAC6DAOTSHR | |
| Hydrochloric Acid SCHEMBL28066263 | 0.92 | ALDH1A1 (0.70) | ALDH1A1HDAC8HDAC6SMN1; SMN2KMT2A | |
| Benzophenone SCHEMBL29263944 | 0.87 | HDAC8 (0.61) | ALDH1A1HDAC8HDAC6SMN1; SMN2MEN1 | |
| 4-Methylbenzoic Acid SCHEMBL31121234 | 0.87 | SMN1; SMN2 (0.61) | ALDH1A1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL3503996 | 0.86 | ALDH1A1 (0.81) | ALDH1A1HDAC8HDAC6TSHRSMN1; SMN2 | |
| Bicarbonate SCHEMBL23420914 | 0.86 | HDAC8 (0.64) | HDAC8HDAC6SMN1; SMN2MEN1KMT2A | |
| Bicarbonate SCHEMBL11577277 | 0.86 | HDAC8 (0.64) | HDAC8HDAC6SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15392980 | 0.84 | ALDH1A1 (0.78) | ALDH1A1HDAC8HDAC6TSHRSMN1; SMN2 | |
| SCHEMBL20846406 | 0.84 | EPHX2 (0.73) | ALDH1A1HDAC8HDAC6SMN1; SMN2KMT2A | |
| Benzylhydrazine SCHEMBL27602656 | 0.83 | IDO1 (0.68) | ALDH1A1DAOTSHRNAPRTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925581-A | Polyethylene pipe with rat bite prevention function and preparation method thereof | 日丰企业（佛山）有限公司 | 2020-11-13 | — | — | CN | claimed |
| CN-122094832-A | Rust-proof film | — | 2026-05-26 | — | — | CN | disclosed |
| EP-4692215-A1 | MODIFIED POLYOLEFIN RESIN COMPOSITION AND USE FOR SAID RESIN COMPOSITION | TOYOBO MC Corporation (JP) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024203664-A1 | MODIFIED POLYOLEFIN RESIN COMPOSITION AND USE FOR SAID RESIN COMPOSITION | 東洋紡エムシー株式会社 | 2024-10-03 | — | — | WO | disclosed |
| CN-111925581-A | Polyethylene pipe with rat bite prevention function and preparation method thereof | 日丰企业（佛山）有限公司 | 2020-11-13 | — | — | CN | disclosed |
| US-4514415-A | ANALGESICS | CIBA GEIGY CORPORATION (US) | 1985-04-30 | — | — | US | disclosed |
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| EP-0107620-A1 | Phenol derivatives | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0082109-A2 | Substituted 2-hydroxyphenylacetic acids and derivatives of them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| EP-0078240-A2 | Lactones | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | disclosed |
| EP-0078241-A2 | Furanes | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | disclosed |