⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811215 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL3776532 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL3778734 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL28612856 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL810661 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL3770995 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL7217484 | 0.74 | — | — | |
| SCHEMBL1097160 | 0.73 | — | — | |
| Iodide SCHEMBL3698424 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL2020474 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215056-B1 | SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES | DU PONT (US) | 2013-10-30 | — | — | EP | disclosed |
| US-8153846-B2 | Sulfur containing fluoroalkyl amines and isocyanates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-10 | — | — | US | disclosed |
| EP-2215056-A2 | SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES | E. I. du Pont de Nemours and Company (US) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009073592-A2 | SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-11 | — | — | WO | disclosed |
| US-20090143608-A1 | SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES | E. I. DU PONT DE NEMOURS AND COMPNAY | 2009-06-04 | — | — | US | disclosed |