Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.77 |
| ▸ | CTSK | P43235 | 11/20 | 0.77 |
| ▸ | CTSL | P07711 | 3/20 | 0.77 |
| ▸ | CTSB | P07858 | 2/20 | 0.77 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944015 | 1.00 | CTSS (0.77) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL6257676 | 0.87 | CTSS (1.00) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6183558 | 0.87 | CTSS (1.00) | CTSSCTSKCTSLCTSB | |
| SCHEMBL996962 | 0.85 | CTSS (0.72) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL10944684 | 0.85 | CTSS (0.72) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL24741085 | 0.85 | CAPN1 (0.74) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL18414075 | 0.85 | CTSS (0.72) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL13764937 | 0.85 | CTSS (0.72) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL7308763 | 0.84 | CTSS (0.70) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL9787700 | 0.83 | CTSS (0.69) | CTSSCTSKCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515920-A | Synthesis of peptides and proteins | THE ROCKEFELLER UNIVERSITY (US) | 1985-05-07 | — | — | US | disclosed |