Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.69 |
| ▸ | CTSK | P43235 | 7/20 | 0.69 |
| ▸ | CTSL | P07711 | 2/20 | 0.69 |
| ▸ | CTSB | P07858 | 1/20 | 0.69 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.67 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12653371 | 0.88 | CAPN1 (0.66) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL1237289 | 0.88 | CAPN1 (0.66) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL22498643 | 0.87 | CTSS (0.52) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL22498641 | 0.87 | CTSS (0.52) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL18941377 | 0.86 | CTSS (0.68) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL17449484 | 0.86 | CTSS (0.68) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL22507116 | 0.86 | CTSS (0.57) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL28969921 | 0.86 | CTSS (0.68) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL7302264 | 0.86 | CTSS (0.68) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL10944684 | 0.86 | CTSS (0.72) | CTSSCTSKCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997950-A | Antisecretory | MURPHY RICHARD FINBAR (US) | 1991-03-05 | — | — | US | disclosed |