Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2271997 | 0.95 | TSHR (0.43) | TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL153638 | 0.84 | TSHR (0.46) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 | |
| Bromide SCHEMBL31547794 | 0.81 | TSHR (0.43) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL702940 | 0.81 | TSHR (0.43) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 | |
| Fluoride SCHEMBL27639893 | 0.81 | TSHR (0.43) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10423271 | 0.81 | TSHR (0.43) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL706848 | 0.81 | TSHR (0.43) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL704491 | 0.81 | TSHR (0.43) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2140790 | 0.81 | TSHR (0.43) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28217587 | 0.81 | TSHR (0.43) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068813-B1 | FUNGICIDAL 1,2,4-TRIAZOLE AND IMIDAZOLE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-09-25 | — | — | EP | disclosed |
| US-4510136-A | A 1-SILYLMETHYL DERIVATIVE; AGRICULTURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-09 | — | — | US | disclosed |
| US-4496551-A | Fungicidal imidazole derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0068813-A2 | Fungicidal 1,2,4-triazole and imidazole derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |