Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943497 | 0.94 | IMPDH2 (0.50) | IMPDH2KIF11RAB9ANPC1KDM4E | |
| SCHEMBL10943155 | 0.91 | IMPDH2 (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10942925 | 0.82 | NPC1 (0.50) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL10945643 | 0.81 | KDM4E (0.38) | IMPDH2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL10942657 | 0.80 | KDM4E (0.40) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL10944475 | 0.79 | IMPDH2 (0.46) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10949475 | 0.79 | NPC1 (0.47) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL10941059 | 0.78 | ABCG2 (0.55) | IMPDH2KIF11RAB9ANPC1KDM4E | |
| SCHEMBL10947281 | 0.78 | PTPN7 (0.36) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL10945712 | 0.76 | NPC1 (0.61) | RAB9ANPC1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |