Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 8/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943497 | 0.98 | IMPDH2 (0.50) | IMPDH2ABCG2GAAMEN1KMT2A | |
| SCHEMBL10944270 | 0.91 | GABRA1 (0.41) | IMPDH2ABCG2GAAMEN1KMT2A | |
| SCHEMBL10941774 | 0.86 | ABCG2 (0.51) | IMPDH2ABCG2GAAMEN1KMT2A | |
| SCHEMBL10941059 | 0.84 | ABCG2 (0.55) | IMPDH2ABCG2GAAMEN1KMT2A | |
| SCHEMBL10942850 | 0.82 | IMPDH2 (0.53) | IMPDH2ABCG2GAAMEN1KMT2A | |
| SCHEMBL10942326 | 0.79 | IMPDH2 (0.56) | IMPDH2ABCG2GAAMEN1KMT2A | |
| SCHEMBL10948658 | 0.79 | NPC1 (0.58) | MEN1KMT2APOLBNPC1KDM4E | |
| SCHEMBL10947215 | 0.79 | IMPDH2 (0.50) | IMPDH2ABCG2GAAMEN1KMT2A | |
| SCHEMBL10990724 | 0.78 | MAPT (0.45) | GAAMEN1KMT2APOLBNPC1 | |
| SCHEMBL10945075 | 0.77 | KDM4E (0.48) | GAAMEN1KMT2APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |