Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095002 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2TAAR1 | |
| SCHEMBL8523819 | 0.75 | ALDH1A1 (0.62) | GAASMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL8523818 | 0.75 | ALDH1A1 (0.62) | GAASMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL12756955 | 0.75 | ALDH1A1 (0.62) | GAASMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL26951412 | 0.73 | — | — | |
| SCHEMBL12756953 | 0.73 | SRC (0.47) | SRCGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL13397720 | 0.72 | SRC (0.61) | SRCGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL16208860 | 0.71 | KDM4E (0.30) | — | |
| SCHEMBL1095279 | 0.69 | — | — | |
| SCHEMBL213506 | 0.67 | GAA (0.40) | SRCGAACHRM2CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188553-A1 | COMPOUNDS | The Provost, Fellows, Foundation Scholars and the other members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth, (IE) | 2023-06-07 | — | — | EP | claimed |
| US-8153791-B2 | substituted pyrimidine compoundssuch as 4-amino-6-(3-chloro-4-fluoro-phenylamino)-pyrimidine-5-carbaldehyde O-methyl oxime, used for treating, preventing or ameliorating a chronic or acute protein kinase mediated diseasea, disorders or conditions | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-04-10 | — | — | US | claimed |
| CN-116783197-A | Compounds of formula (I) | 都柏林圣三一学院教务长、研究员、基金会学者及董事会其他成员 | 2023-09-19 | — | — | CN | disclosed |
| EP-4188553-A1 | COMPOUNDS | The Provost, Fellows, Foundation Scholars and the other members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth, (IE) | 2023-06-07 | — | — | EP | disclosed |
| US-8153791-B2 | substituted pyrimidine compoundssuch as 4-amino-6-(3-chloro-4-fluoro-phenylamino)-pyrimidine-5-carbaldehyde O-methyl oxime, used for treating, preventing or ameliorating a chronic or acute protein kinase mediated diseasea, disorders or conditions | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-04-10 | — | — | US | disclosed |