Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944848 | 1.00 | PPARG (0.51) | PPARGPPARAPTPN1L3MBTL1ACE | |
| SCHEMBL10947518 | 0.85 | PPARG (0.49) | PPARGPPARAPTPN1L3MBTL1ACE | |
| SCHEMBL10949524 | 0.85 | PPARG (0.49) | PPARGPPARAPTPN1L3MBTL1ACE | |
| SCHEMBL10946341 | 0.79 | ALDH1A1 (0.51) | PPARGPPARAL3MBTL1EPHX1KMT2A | |
| SCHEMBL10946335 | 0.79 | ALDH1A1 (0.51) | PPARGPPARAL3MBTL1EPHX1KMT2A | |
| SCHEMBL5377347 | 0.77 | PPARG (0.56) | PPARGPPARAACECA2LDHA | |
| SCHEMBL9461442 | 0.77 | PTPN1 (0.73) | PTPN1ACECA2LDHAKMT2A | |
| SCHEMBL9461443 | 0.77 | PTPN1 (0.73) | PTPN1ACECA2LDHAKMT2A | |
| SCHEMBL9461988 | 0.77 | PTPN1 (0.73) | PTPN1ACECA2LDHAKMT2A | |
| SCHEMBL7101476 | 0.77 | L3MBTL1 (0.55) | PPARGPPARAL3MBTL1ACEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558150-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0158947-A2 | Amino thiol dipeptides | E.R. Squibb & Sons, Inc. (US) | 1985-10-23 | — | — | EP | disclosed |
| US-4500518-A | ANALGESICS, HYPTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1985-02-19 | — | — | US | disclosed |