Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829258 | 0.85 | TSHR (0.42) | THRBTSHRALDH1A1TDP1 | |
| Hydroxyl Radical SCHEMBL28295756 | 0.83 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL7521412 | 0.81 | TSHR (0.62) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL27357 | 0.81 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL27955551 | 0.79 | TSHR (0.60) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16573 | 0.79 | — | — | |
| SCHEMBL21772349 | 0.79 | TSHR (0.69) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10599895 | 0.78 | TSHR (0.70) | THRBTSHRALDH1A1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL8572537 | 0.77 | TSHR (0.67) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL31029924 | 0.77 | TSHR (0.67) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507452-A | HIGH OXYGEN PERMEABILITY, REDUCED TENDENCY FOR BIOLOGICAL CONTAMIN | McCarry, John D. (US) | 1985-03-26 | — | — | US | disclosed |