Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944852 | 0.85 | THRB (0.49) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL3994371 | 0.82 | — | — | |
| SCHEMBL3478021 | 0.82 | TSHR (0.45) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL52703 | 0.80 | TSHR (0.44) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL26129017 | 0.80 | TSHR (0.44) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL3476011 | 0.80 | TSHR (0.44) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL4096843 | 0.80 | TSHR (0.44) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL1521007 | 0.78 | THRB (0.44) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL4829187 | 0.78 | TSHR (0.42) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL5470639 | 0.78 | TSHR (0.42) | TSHRTHRBHCAR2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606250-A1 | IMPROVED SCRATCH AND MAR RESISTANT LOW VOC COATING COMPOSITION | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-12-21 | — | — | EP | claimed |
| WO-2004083178-A1 | IMPROVED SCRATCH AND MAR RESISTANT LOW VOC COATING COMPOSITION | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2004-09-30 | — | — | WO | claimed |
| EP-1095083-B1 | COATING CONTAINING HYDROXY CONTAINING ACRYLOSILANE POLYMER TO IMPROVE MAR AND ACID ETCH RESISTANCE | DU PONT (US) | 2004-09-29 | — | — | EP | claimed |
| US-20040185269-A1 | Scratch and mar resistant low VOC coating composition | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-09-23 | — | — | US | claimed |
| EP-1205503-B1 | Coating composition having improved acid etch resistance | DU PONT (US) | 2004-08-25 | — | — | EP | claimed |
| EP-1205503-A1 | Coating composition having improved acid etch resistance | E.I. du Pont de Nemours and Company (US) | 2002-05-15 | — | — | EP | claimed |
| US-6379807-B1 | ACRYLOSILANE COPOLYMER FILM FORMING BINDER; CLEAR COATS FOR AUTOMOBILES; ANTISOILANTS; POLYISOCYANATE AND MELAMINE CROSSLINKING AGENT | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-04-30 | — | — | US | claimed |
| EP-0868460-B1 | COATING CONTAINING ACRYLOSILANE POLYMER TO IMPROVE MAR AND ACID ETCH RESISTANCE | DU PONT (US) | 2001-11-07 | — | — | EP | claimed |
| EP-1095083-A1 | COATING CONTAINING HYDROXY CONTAINING ACRYLOSILANE POLYMER TO IMPROVE MAR AND ACID ETCH RESISTANCE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-05-02 | — | — | EP | claimed |
| WO-1999067314-A1 | COATING CONTAINING HYDROXY CONTAINING ACRYLOSILANE POLYMER TO IMPROVE MAR AND ACID ETCH RESISTANCE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-12-29 | — | — | WO | claimed |
| US-5985463-A | POLYISOCYANATE CROSSLINKING AGENT; AUTOMOBILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-16 | — | — | US | claimed |
| EP-0868460-A1 | COATING CONTAINING ACRYLOSILANE POLYMER TO IMPROVE MAR AND ACID ETCH RESISTANCE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-10-07 | — | — | EP | claimed |
| US-5684084-A | AUTOMOBILE FINISHES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-04 | — | — | US | claimed |
| WO-1997022647-A1 | COATING CONTAINING ACRYLOSILANE POLYMER TO IMPROVE MAR AND ACID ETCH RESISTANCE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-06-26 | — | — | WO | claimed |
| EP-0174368-A1 | SILICONE HYDRIDE CONTACT LENS AND POLYMER | MC CARRY, John D. (US) | 1986-03-19 | — | — | EP | claimed |
| WO-1985003940-A1 | SILICONE HYDRIDE CONTACT LENS AND POLYMER | MC CARRY, JOHN, D. (US) | 1985-09-12 | — | — | WO | claimed |
| US-20230381016-A1 | OPHTHALMIC COMPOSITION AND DELIVERY DEVICE THEREOF | Sydnexis, Inc. | 2023-11-30 | — | — | US | disclosed |
| US-20230038369-A1 | FLUORINE-FREE OIL REPELLENT COATING, METHODS OF MAKING SAME, AND USES OF SAME | CORNELL UNIVERSITY | 2023-02-09 | — | — | US | disclosed |
| EP-0174368-A1 | SILICONE HYDRIDE CONTACT LENS AND POLYMER | MC CARRY, John D. (US) | 1986-03-19 | — | — | EP | disclosed |
| WO-1985003940-A1 | SILICONE HYDRIDE CONTACT LENS AND POLYMER | MC CARRY, JOHN, D. (US) | 1985-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381016-A1 | OPHTHALMIC COMPOSITION AND DELIVERY DEVICE THEREOF | CHRM3, CHRM2, CHRM4 | TSHR 497/4885THRB 566/4885HCAR2 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.