Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947434 | 0.95 | KDM4E (0.32) | KDM4EPOLB | |
| SCHEMBL12348441 | 0.89 | GAA (0.31) | — | |
| SCHEMBL10945676 | 0.86 | CA1 (0.33) | CA1CA2CA9KDM4EPOLB | |
| SCHEMBL301807 | 0.83 | CA1 (0.35) | CA1CA2CA9KDM4E | |
| SCHEMBL13880635 | 0.80 | KDM4E (0.35) | CA1CA2CA9KDM4E | |
| SCHEMBL7868497 | 0.78 | CA1 (0.35) | CA1CA2CA9 | |
| SCHEMBL9215885 | 0.76 | CA1 (0.35) | CA1CA2CA9KDM4E | |
| SCHEMBL20745709 | 0.74 | ALDH1A1 (0.35) | KDM4E | |
| SCHEMBL31277708 | 0.73 | KDM4E (0.35) | CA9KDM4E | |
| SCHEMBL12325394 | 0.71 | MGAM (0.34) | CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | claimed |
| EP-0069907-B1 | PROCESS FOR PREPARING M-CHLORO-SUBSTITUTED ANILINES | BAYER AG (DE) | 1985-08-28 | — | — | EP | disclosed |
| US-4532350-A | Process for the selective preparation of meta-chloroanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-07-30 | — | — | US | disclosed |
| US-4495368-A | Process for the preparation of meta-halogenoanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-01-22 | — | — | US | disclosed |
| US-4460788-A | Process for preparation of anilines which are m-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-17 | — | — | US | disclosed |
| US-4429156-A | Process for the preparation of m-halogen-substituted anilines | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| US-4418213-A | HYDRODEHALOGENATION LEWIS ACID AND NOBLE METAL CATALYSTS | RHONE-POULENC AGROCHIMIE (FR) | 1983-11-29 | — | — | US | disclosed |
| EP-0069907-A2 | Process for preparing m-chloro-substituted anilines | BAYER AG (DE) | 1983-01-19 | — | — | EP | disclosed |
| US-4351959-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-09-28 | — | — | US | disclosed |
| US-4340759-A | Process for the preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-07-20 | — | — | US | disclosed |
| EP-0051782-A1 | Process for the manufacture of m-halogenated anilines | BAYER AG (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-4324914-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-04-13 | — | — | US | disclosed |
| US-4193937-A | DECHLORINATION OF CHLOROANILINES, SELECTIVE HYDROGENATION CATALYSTS OF NOBLE METAL AND SULFUR | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | disclosed |