Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.47 |
| ▸ | GSR | P00390 | 2/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903520 | 1.00 | SLC1A1 (0.47) | SLC1A1SLC1A3SLC1A2GSRGRM8 | |
| SCHEMBL1529903 | 0.88 | SLC7A5 (0.34) | SLC1A1SLC1A3SLC1A2GSRGRM8 | |
| SCHEMBL1444867 | 0.86 | SLC1A1 (0.50) | SLC1A1SLC1A3SLC1A2GSRGRM8 | |
| SCHEMBL4385421 | 0.85 | SLC1A1 (0.43) | SLC1A1SLC1A3SLC1A2GSRGRM8 | |
| SCHEMBL27909404 | 0.84 | SLC1A1 (0.48) | SLC1A1SLC1A3SLC1A2GSRGRM8 | |
| SCHEMBL8574771 | 0.84 | SLC7A5 (0.37) | SLC1A1SLC7A5 | |
| SCHEMBL7763893 | 0.84 | GABRP (0.47) | SLC1A1CYP1A2KMT2ASLC7A5 | |
| SCHEMBL15658562 | 0.83 | SLC7A5 (0.42) | SLC1A1SLC1A3SLC1A2CYP1A2BLM | |
| SCHEMBL542262 | 0.83 | SLC7A5 (0.42) | SLC1A1SLC1A3SLC1A2CYP1A2BLM | |
| SCHEMBL28252494 | 0.83 | SLC1A1 (0.47) | SLC1A1SLC1A3SLC1A2GSRGRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114480393-A | Globulin gene therapy for the treatment of hemoglobinopathies | 纪念斯隆-凯特琳癌症中心 | 2022-05-13 | — | — | CN | disclosed |
| CN-114457076-A | Globulin gene therapy for the treatment of hemoglobinopathies | 纪念斯隆-凯特琳癌症中心 | 2022-05-10 | — | — | CN | disclosed |
| CN-107208093-B | Globulin gene therapy for the treatment of hemoglobinopathies | 纪念斯隆-凯特琳癌症中心 | 2022-03-01 | — | — | CN | disclosed |
| US-10175233-B2 | Biomarkers for cardiovascular diseases and methods using the same | METABOLON, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| CN-107208093-A | Globulin gene therapy for the treatment of hemoglobinopathies | 纪念斯隆-凯特琳癌症中心 | 2017-09-26 | — | — | CN | disclosed |
| US-20160178620-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2016-06-23 | — | — | US | disclosed |
| WO-2016048828-A1 | GENETICALLY MODIFIED MICROBES FOR THE BIOLOGICAL CONVERSION OF CARBONACEOUS MATERIALS TO ISOBUTANOL AND ISOAMYL ALCOHOL | CIRIS ENERGY, INC. (US) | 2016-03-31 | — | — | WO | disclosed |
| US-9250225-B2 | Biomarkers for insulin resistance and methods using the same | METABOLON, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150005195-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2015-01-01 | — | — | US | disclosed |
| US-8809008-B2 | Biomarkers for impaired glucose tolerance and methods using the same | METABOLON, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8546098-B2 | Biomarkers for monitoring insulin resistance and methods using the same | METABOLON, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120208215-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-8187830-B2 | Method for determining insulin sensitivity with biomarkers | METABOLON, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| EP-2424880-A1 | IMMUNOREACTIVE EHRLICHIA P120/P140 EPITOPES AND USES THEREOF | Research Development Foundation (US) | 2012-03-07 | — | — | EP | disclosed |
| WO-2011146683-A1 | METHODS AND REAGENTS FOR METABOLOMICS AND HISTOLOGY IN A BIOLOGICAL SAMPLE AND A KIT FOR THE SAME | METABOLON, INC. (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2010126993-A1 | IMMUNOREACTIVE EHRLICHIA P120/P140 EPITOPES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2010-11-04 | — | — | WO | disclosed |
| US-20090155826-A1 | Biomarkers for pre-diabetes, cardiovascular diseases, and other metabolic-syndrome related disorders and methods using the same | METABOLON, INC. (US) | 2009-06-18 | — | — | US | disclosed |
| US-20020001804-A1 | Genomic analysis of tRNA gene sets | TAO BIOSCIENCES, LLC | 2002-01-03 | — | — | US | disclosed |
| US-5770560-A | TREATING REDUCED HEMOGLOBIN OXYGEN AFFINITY IN MAMMALS | Fischer, James J. (US) | 1998-06-23 | — | — | US | disclosed |
| US-5173426-A | Pure polynucleotide; for increasing tissue oxygenation in patients | YALE UNIVERSITY (US) | 1992-12-22 | — | — | US | disclosed |