Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRE | P78334 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574771 | 0.89 | SLC7A5 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15658562 | 0.88 | SLC7A5 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL542262 | 0.88 | SLC7A5 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1529903 | 0.85 | SLC7A5 (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL109454 | 0.84 | SLC1A1 (0.47) | SLC7A5SLC1A1CYP1A2KMT2A | |
| SCHEMBL27903520 | 0.84 | SLC1A1 (0.47) | SLC7A5SLC1A1CYP1A2KMT2A | |
| SCHEMBL28772435 | 0.82 | ALDH1A1 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3285174 | 0.82 | ALDH1A1 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1535416 | 0.79 | SLC7A5 (0.42) | SLC7A5ALDH1A1SLC1A1SLC15A1CYP1A2 | |
| SCHEMBL599033 | 0.78 | SLC7A5 (0.41) | SLC7A5SLC15A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098487-A1 | POLYNUCLEOTIDES AND POLYPEPTIDES LINKED TO BLOOD PRESSURE REGULATION AND/OR FATIGUE | THE UNIVERSITY OF QUEENSLAND (AU) | 2001-12-27 | — | — | WO | disclosed |